newspaper mockup Gene test shows more breast cancer patients can skip chemo // WORLD BREKING NEWS

Gene test shows more breast cancer patients can skip chemo // WORLD BREKING NEWS
TAMPA, USA: The majority of women with a common form of breast cancer may be able to skip chemotherapy after surgery, based on their score on a genetic test, researchers said Sunday.
As many as 65,000 women in the United States alone could be impacted by the study, described as the largest breast cancer trial to date, released at the American Society of Clinical Oncology annual meeting in Chicago.
Until now, women have faced a great deal of uncertainty about whether to add chemo to hormone therapy after a diagnosis with hormone-receptor positive, HER-2 negative breast cancer when found at an early stage before it has spread to the lymph nodes.
“With results of this ground-breaking study, we now can safely avoid chemotherapy in about 70 percent of patients who are diagnosed with the most common form of breast cancer,” said co-author Kathy Albain, an oncologist at Loyola Medicine.
“For countless women and their doctors, the days of uncertainty are over.”
A 21-gene test called Oncotype Dx that has been around since 2004 has helped guide some decisions, post-surgery.
A high recurrence score, above 25, means chemo is advised to ward off a recurrence while a low score, below 10, means it is not.
The current study involved more than 10,000 women and focused on those whose scores were in the middle range, from 11 to 25.
Patients, aged 18 to 75, were randomly assigned to receive chemotherapy followed by hormonal therapy or hormone therapy alone.
Then, researchers studied the outcomes, including whether or not cancer recurred, and overall survival.
“For the entire study population with gene test scores between 11 and 25 — and especially among women aged 50 to 75 — there was no significant difference between the chemotherapy and no chemotherapy groups,” said the findings, published in the New England Journal of Medicine.
The results show that all women over 50 with a recurrence score of 0 to 25 can be spared chemotherapy and its toxic side effects.
For women under 50 with a score of 0 to 15, chemo could be skipped.
However, among younger women with scores 16 to 25, outcomes were slightly better in the chemotherapy group, so in those cases doctors may urge patients to consider a chemo regimen.
The results “should have a huge impact on doctors and patients,” Albain said.
“We are de-escalating toxic therapy.”
According to first author Joseph Sparano of Montefiore Medical Center in Bronx, New York, “any woman with early stage breast cancer 75 or younger should have the test and discuss the results” with her doctor.
Breast cancer is the leading cause of cancer death in women worldwide, causing some 1.7 million new cases annually and over half a million deaths.
The study’s primary funding came from the US National Institutes of Health.

newspaper mockup Gene test shows more breast cancer patients can skip chemo // WORLD BREKING NEWS
1 Likes	1 Dislikes
11 views views	followers
News & Politics	Upload TimePublished on 3 Jun 2018

Related keywords

top stories today uk,breaking news today earthquake,breaking news today in america,latest news today 2019,news headlines uk,news world,news headlines pakistan,news headlines australia,top stories today pakistan,top stories today google,top stories today daily mail,breaking news thailand,donald trump age,news headlines india,news headlines abc,newsame,news turkey,news headlines rte,current news in nigeria,breaking news today youtube channel,world news today usa,latest news today in hindi,current news in ghana,breaking news vector,news headlines ireland,newsroom,current news india pakistan,breaking news live,news headlines sports,top stories today canada,breaking news cnbc,current news 2019,news google,foreign policy examples,current news in india,world news today uk,breaking news bangkok,newsnow,current news in tamilnadu,top stories today zimbabwe,breaking news today eddie garcia,breaking news cnn,donald trump net worth,current news in tamil,top stories today show,news in level,donald trump wife,foreign policy とは,world news today cnn,world news today in tamil,latest news today in nigeria,breaking news nation,top stories today in nigeria,newspaper,news haber,donald trump today,latest news today in usa,breaking news world,world news today google,breaking news (2004),top stories today cnn,foreign policy research institute,news headlines bbc,breaking news today cebu,donald trump quotes,foreign policy 雑誌,world news today guardian,newspaper theme,top stories today india,latest news today local,donald trump when they see us,breaking news intro,foreign policy issues,breaking news ไทยรัฐ,foreign policy definition,donald trump birthday,donald trump hair,latest news today on iran,breaking news today in hindi,donald trump jr,foreign policy food truck,news headlines world,top stories today fox news,top stories today south africa,world news today japan,news headlines south africa,latest news today google,world news today video,top stories today in mzansi,donald trump news,latest news today cnn,newsweek,breaking news english,top stories today youtube channel,world news today bbc,donald trump parents,latest news today in world,top stories today's news,latest news today in tamil,top stories today world,donald trump 2020,donald trump polls,current news pakistan,breaking news hong kong,world news today earthquake,current news in hindi,latest news today nyc,current news on kashmir,current news around the world,breaking news today philippines,breaking news ไทย,newsroom izle,top stories today from guyana times,latest news today in english,world news today in english,breaking news today earthquake philippines,world news today headlines,breaking news today in bohol philippines,news in levels,news ne demek,donald trump wiki,current news in afghanistan,breaking news today tagalog,breaking news เนชั่น,latest news today yahoo,donald trump education,breaking news today gma,breaking news today kenya,news point,news headlines in nigeria,world news todays,news corporation,top stories today usa,breaking news today english,donald trump signature,breaking news today in nigeria,latest news today india,latest news today earthquake,world news today live,breaking news today sports,news bg,news headlines of today in hindi,latest news today guyana,current news aaj tak,latest news today in telugu,latest news today on youtube,foreign policy 意味,world news today reuters,foreign policy in focus,news headlines today ireland,breaking news today in mexico,foreign policy nixon,world news today now,foreign policy analysis,news headlines today uk,world news today in hindi,news headlines live,latest news today philippines,current news in the world,news headlines in hindi,breaking news แปลว่า,breaking news today kapa,current news mumbai,current news in the philippines,donald trump children,news headlines melbourne,breaking news today world,breaking news today in india,foreign policy of pakistan,breaking news คือ,latest news today fox,world news today tagalog,breaking news today live,donald trump height,donald trump approval rating,current news in kenya,current news in uganda,newscientist,news headlines traduccion,newsela,donald trump kids,today's top stories,news headlines today,breaking news bbc,breaking news football,top stories today sports,world news today australia,current news in english,world news today venezuela,breaking news forex,current news in south africa,